Chungnam region accounts for the largest SOX (22.8%) emission with the second-largest NOX (10.8%) emission in Korea due to the integration of many large industrial sources including a steel mill, coal-fired power plants, and petrochemical complex. Air pollutants emitted by large industrial sources can cause harmful problems to humans and the environment. Thus, it is necessary to understand dispersion patterns of air pollutants from large industrial sources in Chungnam to characterize atmospheric contamination in Chungnam and the surrounding area. In this study, seasonal atmospheric dispersion characteristics for SOX, NOX, and PM2.5 from ten major point sources in Chungnam were evaluated using HYSPLIT 4 model, and their contributions to SO2, NO2 concentrations in the regions near the source areas were estimated. The predictions of the HYSPLIT 4 model show a seasonal different dispersion pattern, in which air pollutants were dispersed toward the southeast in winter while, northeast in summer. In summer, due to weaker wind speed, air pollutants concentrations were higher than in winter, and they were dispersed to the metropolitan area. The local emissions of air pollutants in Taean area had a greater influence on the ambient SO2 and NO2 concentrations at Taean, whereas SOX and NOX emissions from large sources located at Seosan showed relatevely little effect on the ambient ambient SO2 and NO2 concentrations at Seosan.